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The largest current study of an AIDS vaccine, involving 2,500 people, is being stopped. After an oversight committee took a preliminary peek at the results this past Monday, they concluded there was no way would show that the vaccine prevents HIV infection.

Failure of latest HIV vaccine test: A 'huge disappointment'

Date: 26 April 2013

Source: National Public Radio

AUTHOR: Richard Knox

The largest current study of an AIDS vaccine, involving 2,500 people, is being stopped. After an oversight committee took a preliminary peek at the results this past Monday, they concluded there was no way would show that the vaccine prevents HIV infection. Nor would the vaccine suppress the wily virus among people who get infected despite being vaccinated.

"It (HVTN-505) was a huge disappointment," says study leader , who learned the bad news at 1:45 Monday afternoon.

Hammer tells Shots the blow was all the more crushing because just a month earlier the had met its goal for participants.

"It was a big traumatic event to put all this effort in and then have the vaccine trial stop because of futility a month after we completed enrollment," Hammer says. He's chief of infectious diseases at Columbia University College of Physicians and Surgeons and a leading AIDS researcher who's been fighting the virus since the pandemic's beginning.

Participants are being notified that no more shots will be given. They will be followed for up to five more years to glean as much insight as possible from the $77 million, federally financed project.

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